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2681 CORE ACCELERATOR

Where Capital Meets Rural Innovation

Named for the crossroads of I-26 and I-81, 2681 Core is where entrepreneurship and investment intersect in Northeast Tennessee.

2681 Core is anchored by the Research Corporation's Center for Innovation. Through the Accelerate Appalachia program, we give regional founders and small businesses the resources, mentorship, and capital to grow.

How we accelerate companies


  • Launch of the 2681 Accelerator
  • The region's first member-managed regional investment fund
  • Nationally recognized Soft Landings through the ETSU iLab
  • Technology transfer from ETSU, via Launch Tennessee's commercialization consortium

A homegrown investment fund


2681 created the region's first member-managed regional investment fund, putting regional capital behind regional companies. The Research Corporation also received a $1 million grant to establish a regional Rural Innovation and Entrepreneurship Alliance.

Backed by the region


Bank of TennesseeBallad HealthUS AntibioticsNiswonger FoundationLaunch TennesseeBAE Systems Ordnance SystemsNETWORKS Sullivan PartnershipNortheast State Community College

Founder or investor?

Join a cohort or back the fund.

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